Role of vitamin D in chronic hepatitis C
نویسندگان
چکیده
منابع مشابه
Role of vitamin D in chronic hepatitis C
Abbreviations: CHC, chronic hepatitis C; CYP, cytochrome P450; HCV, hepatitis C virus; IL, interleukin; Peg, pegylated interferon alfa; RBV, ribavirin; SVR, sustained virologic response; VDRs, vitamin D receptors; Th, helper T cell; 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)D, 1,25-dihydroxyvitamin D Corresponding author: Tae Yeob Kim Department of Internal Medicine, Hanyang University Guri Hospita...
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Although initially identified as a calcium homeostatic hormone, vitamin D is now known to have pleiotropic functions, dealing with both innate and adaptative immunity. Calcitriol mediates its biological effects by binding to the vitamin D receptor (VDR), which is expressed not only by intestine, bone and kidney but also on cell membranes of T lymphocytes, B lymphocytes, dendritic cells and macr...
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BACKGROUND Vitamin D has immunomodulatory properties, exerts an anti-hepatitis C virus (HCV) effect in vitro and improves response to interferon-based therapy in patients with chronic hepatitis C (CHC). Low serum levels of 25(OH) vitamin D [25(OH)D] are frequently found in CHC patients and seem to be related to more advanced stages of liver fibrosis. The study aims to establish the incidence of...
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UNLABELLED Vitamin D deficiency seems to predict the unsuccessful achievement of sustained viral response (SVR) after antiviral treatment in hepatitis C virus (HCV) difficult-to-treat genotypes. Vitamin D binding protein (GC) gene polymorphisms are known to influence vitamin D levels. This study was performed to assess whether the interaction between basal circulating vitamin D and the GC polym...
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Introduction: Long-term stress disturbs HPA axis and increases glucocorticoids release, which disturbs neural plasticity in the hippocampus and may lead to learning and memory deficits. Noticeably, vitamin D plays a protective role in the nervous system and has receptors in the hippocampus. This behavioral study investigates the possible protective role of vitamin-D against the negative effects...
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ژورنال
عنوان ژورنال: The Korean Journal of Hepatology
سال: 2011
ISSN: 1738-222X
DOI: 10.3350/kjhep.2011.17.2.170